When Vyapar is the better choice
If your business is mostly retail or wholesale billing with stock and accounting, and print jobs are a small part of it, a general app like Vyapar may suit you better.
When PrintoShop is the better choice
If most of your income comes from printing work, you need to track each job from quotation to delivery. PrintoShop gives you job cards, production stages, product-wise status, CDR file tracking and a customer tracking link, connected to GST billing and payments.
Can I use both?
Yes. Some printing businesses keep accounting where their accountant prefers and run all print jobs, quotations and customer bills in PrintoShop. PrintoShop also offers Tally export for your accountant.